APP and Alzheimer disease: In the present study, we analyzed whether the expression of APP is regulated by miRNAs such as miR-101-3p, miR-144-3p, miR-153-3p, and miR-381-3p in a Chinese Han patient population with AD, and whether the expression regulation was related to the polymorphisms at the APP 3′UTR-534G/A, -369C/G, and -118C/A loci.