Black SSc/SRC cases were also more likely to have consistently elevated prediagnostic Ro60 autoantibody over time in addition to simultaneously elevated La autoantibody (>30,000 LU), and RNP autoantibody (>30,000 LU) than black SSc/no SRC disease controls [40% (4/10) vs. 6% (1/18), p = 0.04 for both]. The gene discussed is SSB; the disease is systemic sclerosis.