NPPB and heart valve disorder: More intense treatment might be considered at high NT-proBNP levels, whether it be pharmacological treatment, such as increasing the dose of diuretic drugs in order to achieve decongestion, titration of ACEI/ARB dose, exchanging ACEI/ARB for ARNI [19], or non-pharmacological treatment, such as revascularisation procedures in coronary artery disease [20], correction of valvular heart disease or cardiac resynchronisation therapy [1].