One of the hallmarks of various cancer cells is the aberrant expression of cyclooxygenase 2 (COX-2) [9–12], a key enzyme involved in the metabolism of arachidonic acid and generation of prostaglandin E2 (PGE2), an immune suppressive factor that initiates signals to block T-cell proliferation and secretion of proinflammatory cytokines [13–15]. This evidence concerns the gene PTGS2 and cancer.