Of the five representative actionable mutations for NSCLC examined (EGFR, KRAS, PIK3CA, BRAF, and NRAS), EGFR showed the greatest frequency of variants in the AUSOM database (21.9%), while KRAS showed the greatest frequency of variants in the TCGA database (20.2%; Figure 4a). This evidence concerns the gene PIK3CA and non-small cell lung carcinoma.