SIGLEC1 and Autoimmunity: M1Mo identified at MI-day 3 were also low or negative for other MΦ markers Siglec1, Mrc1, Maf, Trem2 and Mertk, the latter involved in phagocytosis (Figure 2—figure supplement 1A) (Bajpai et al., 2018), and C1 complement genes C1qa, b and c (Figure 2C), which are involved (in addition to complement fixation) in recruitment of new inflammatory cells and protection against autoimmunity (Emmens et al., 2017; Thielens et al., 2017).