We recently reported enhanced expression of YAP/TAZ in a range of non-functioning human pituitary tumours, compared to functioning adenomas, and that Lats1 knock-down in GH3 pituitary mammosomatotropinoma cells results in repression of the Gh and Prl promoters (Xekouki et al., 2019). The gene discussed is PRL; the disease is pituitary tumor.