NFE2L2 and cancer: To determine whether NRF2 transcriptional activity is increased in lung micrometastases, we created a list of 24 NRF2 target genes based on NRF2 chromatin immunoprecipitation-sequencing data curated by Cistrome database (ENCODE Project Consortium, 2012) (Supplementary File 4), and performed GSEA analysis on our cancer cell transcriptomes.