GADD45B and brain cancer: The results indicated that the increasing number of the brain cancer cell lines in the G2/M phase may via CuE‐induced association of CDC2 and the GADD45β complex (Figure 3E), and the disassociation of the CDC2/cyclin B1 complex in GBM8401 and U‐87‐MG cells by CuE can be attributed to GADD45β up‐regulation (Figure 3A‐C).