DMD and Duchenne muscular dystrophy: Duchenne muscular dystrophy (DMD) is an X‐linked recessive disease due to mutations in the dystrophin gene (DMD), the biggest gene of the human genome for which about 4700 different mutations have been reported.30, 31, 32, 33 Dystrophin is an essential component of the dystrophin‐associated protein complex (DAPC), a multiprotein complex located at the sarcolemma and responsible for the mechanical link between the intracellular cytoskeleton and the extracellular matrix; dystrophin ensures the structural and functional integrity of myofibres during contraction.