Purified anti-α-Gal Abs agglutinated and killed ~90% of the parasites (in a concentration-dependent manner) in the absence of complement, which is in agreement with the previous observations of anti-α-Gal Abs purified from acute or chronic ChD patients.15,20,22 To evaluate the ability of purified murine anti-α-Gal IgG Abs to prevent host cell infection and intracellular parasite proliferation, cells were infected and 100 μg/mL of murine anti-α-Gal Abs was added simultaneously. Here, DDX41 is linked to coronary artery disorder.