High parasitemia, uncontrolled inflammation, and necrosis of heart myocytes are some of the main factors that influence the development of myocardial dysfunction in ChD patients.86 In this study, histopathological analyses of heart tissue from mice vaccinated with Galα3LN-HSA+/−LMPLA showed significant downregulation of inflammation and low levels of myocyte necrosis, when compared to the HSA-LMPLA group. This evidence concerns the gene ALB and parasitic infectious disease.