Lim et al. [28] detected Trx-1 and thioredoxin-interacting protein (TXNIP) mRNA expression levels in 68 stage III patients with GC using quantitative reverse transcription PCR and found the high Trx-1 and low TXNIP expression group exhibited a poorer prognosis than the other groups. The gene discussed is TXNIP; the disease is gastric cancer.