PFN2 and neoplasm: Our results demonstrated that the group of mice receiving combination of PFL (10 mg/kg, every day) and paclitaxel (5 mg/kg, every 3rd day) showed significant (p = 0.0012) tumor growth suppression (55%) when compared to paclitaxel, whereas group receiving PFL alone showed 40% of tumor reduction (Fig. 7A).