DANCR and breast cancer: Figure 3B displayed that 216a-mimics could obviously reduce luciferase activity of DANCR-WT, while it had no distinct effects on DANCR-MUT. The results of qRT-PCR showed that breast cancer cells transfected with si-DANCR had higher level of miRNA-216a-5p, implying that inhibiting DANCR expression could lead to the increase of miRNA-216a-5p (Figure 3C). In addition, Figure 3D demonstrated that 216a-inhibitor had abilities to increase DANCR expression, while 216a-mimics had opposite effects on DANCR expression.