Antigen Presentation Pathway, the primary pathway, included 5 genes: NLRC5 (NLR Family CARD Domain Containing 5), HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1), HLA-B (Major Histocompatibility Complex, Class I, B), TAP1 (Transporter 1, ATP Binding Cassette Subfamily B Member) and HLA-DRB5 (Major Histocompatibility Complex, Class II, DR Beta 5) which were found to be associated with obesity in the current study. This evidence concerns the gene NLRC5 and obesity disorder.