APC and ovarian cancer: Recently, for example, cell permeable peptides have been developed against the NEMO – IκB kinase complex for the treatment of cisplatin-resistant ovarian cancer [44], stapled peptide disrupters that unhook β-Catenin from transcription factors have been produced as novel colon cancer agents [45] and colon cancer has also been the target of adenomatous polyposis coli (APC) – Asef disrupters [46] that inhibit the migration and invasion of colon cancer cell lines.