A number of miRNAs directly targeting FOXO mRNAs are also implicated in tumor promotion, growth, and metastasis: for example, FOXO3a mRNA was found to be targeted by miR-182 in lung cancer [71] and melanoma [72]; likewise, it was inhibited by miR-155 in pancreatic cancer, where it resulted in oxidative stress [73]. Here, FOXO3 is linked to neoplasm.