Of interest, this report also provided convincing evidence that beneficial effects of IVIg in fungal infections go beyond neutralization of fungi wherein we found that protective effects of IVIg were associated with reduced Th17 responses and concomitant enhancement of regulatory T cells and IL-10, the mechanisms implicated in the beneficial effects of IVIg in autoimmune conditions [32,33]. The gene discussed is IL10; the disease is fungal infectious disease.