Another study was designed to investigate the antifibrosis effects and possible mechanism of AR injection on bleomycin-induced pulmonary fibrosis in rats and revealed that AR injection could exert protective effects on bleomycin-induced pulmonary fibrosis via downregulating TGF-β1/Notch1 in lung [166] (Figure 57). Here, NOTCH1 is linked to pulmonary fibrosis.