Hypermethylation of RASGRF2 has been associated with recurrence of prostatic cancer [73]; BCL7B is a member of the BCL7 gene family (along with the genes BCL7A and BCL7C), in humans, the decrease in BCL7A expression is associated with development of NHL and epithelial lymphoma [74,75]. This evidence concerns the gene RASGRF2 and Familial prostate cancer.