18F-T807 is the most advanced tau PET tracer in terms of its investigation in vivo, with studies completed in numerous tauopathies including AD and PSP (Holt et al., 2016; Jones et al., 2018; Murugan et al., 2018; Saint-Aubert et al., 2017; Schöll et al., 2016; Smith et al., 2016; Spina et al., 2017; Johnson et al., 2016; Schonhaut et al., 2017; Smith et al., 2018). The gene discussed is MAPT; the disease is Alzheimer disease.