The plasma triglyceride levels in Ldlr‐/‐ rats were 1.8‐fold higher than of the wild‐type, whereas no changes in Ldlr‐/‐ mice has been observed.8 Therefore, the similarity of some hallmark physiological functions between rat and human makes the rat model more suitable than the mouse model for heart disorders are more relevant to human conditions. Here, LDLR is linked to heart disorder.