NEFL and Charcot-Marie-Tooth disease type 4C: Finally, in a small group of full or mock vector-treated Sh3tc2−/− mice (n = 5–7 mice per group), we measured blood NfL levels, an established biomarker for axonal injury/degeneration found to be elevated in sera from CMT patients including two patients with CMT4C (Sandelius et al., 2018).