SALL4 and cancer: SALL4 is a crucial factor for the maintenance of self‐renewal and pluripotency of ESCs, decreased gradually during the embryo development and silenced with the maturation of tissues but restored in both hematological diseases and solid tumors.36, 37 Although aberrant expression of SALL4 has been reported influencing the development and prognosis of various cancers,38, 39 the role of SALL4 in NPC remains unclear.