The direction and magnitude of the association of rs4858889 in SCAP with diabetes in the present study (OR 0.68; 95% CI 0.48‐0.96) are consistent with the findings in a previous study in south Asians (OR 0.84; 95% CI 0.77‐0.91).17 In contrast, another Chinese study did not find a significant association between rs4858889 and diabetes;50 however, that study was a case‐control study and the sample was enrolled from hospitals, hence the study cohort may not be representative of the general population. This evidence concerns the gene SCAP and diabetes mellitus.