Disease phenotypes such as rosette formation are thought to be influenced by the ABO blood group, where by O individuals being lower risk of severe malaria while group A are more predisposed individuals to severe malaria (Barragan et al., 2000; Rowe et al., 2007; Vigan-Womas et al., 2012; Goel et al., 2015; Mancio-Silva and Mota, 2015). Here, ABO is linked to malaria.