The HCMV-specific CD4+ T cell response was significantly lower in HCMV-seropositive SLE patients compared to HCMV-seropositive healthy subjects (0.2700 (IQR 0.0630-0.9200) vs 0.6065 (IQR 0.1368-1.250) HCMV-specific CD4+ T cells/μl; P = 0.0004) (Figure 5(b)). The gene discussed is CD4; the disease is systemic lupus erythematosus.