SNCA and Parkinson disease: Nilotinib significantly reduced the concentration of alpha‐synuclein that is elevated in the blood of PD patients.48, 49, 50, 51 These results are consistent with our previous findings that demonstrated Nilotinib effects on lowering blood alpha‐synuclein in mice.7 There is evidence that autophagy is disregulated in the blood of PD patients,52, 53, 54, 55 and the effects of Nilotinib on autophagy may underlie its effects on plasma alpha‐synuclein.