SST and Alzheimer disease: For example, hippocampal SST/GABA interneurons were implicated in the deficits in Alzheimer’s disease (AD) in a recent study using a transgenic mouse model of AD (Schmid et al., 2016) and both a loss and abnormal function of SST/GABA interneurons in ventral hippocampus is also implicated in the cognitive symptomology of schizophrenia in studies of animal models of memory deficits (Lodge et al., 2009; Nakazawa et al., 2012).