Modeling the association of CSF Aβ, total tau (ttau), phosphorylated tau (ptau), and melanotransferrin (MTf) with neuroimaging measures of the hippocampus in cognitively normal (CN), mild cognitive impairment (MCI) or Alzheimer’s disease (AD) (Supplementary Figure 3). Here, MELTF is linked to early-onset autosomal dominant Alzheimer disease.