RIN1 and melanoma: The expression of Ras and Rab interactor 1 (RIN1) expression increases and is related to poor prognosis in many tumors, including non-small cell lung cancer (Wang et al., 2012), melanoma (Fang et al., 2012), gastric adenocarcinoma (Yu et al., 2012) and renal cancer (Wei et al., 2015).