High RIN1 expression is related to tumor progression and poor prognosis in bladder urothelial carcinoma (Shan et al., 2012), gastric adenocarcinoma (Yu et al., 2012) , melanoma (Fang et al., 2012) and non-small cell lung cancer (Wang et al., 2012). The gene discussed is RIN1; the disease is non-small cell lung carcinoma.