Moreover we found that glucose may greatly modulate cancer cell proliferation like in hepatocellular carcinoma cells through LKB1/NADPH Oxidase signaling [22] and other studies are in progress on several cancer cell models in order to depict the signaling pathways dysregulated according to crosstalk between glucose, insulin and fatty acid signaling in cancer cells (Berger & Géloën, manuscripr in preparation). Here, STK11 is linked to hepatocellular carcinoma.