To verify whether the ATF1 rs11169571 affects its expression in the NPC cell, the luciferase reporter vector of the ATF1 gene's 3′‐UTR with either ‐C or ‐T allele of rs11169571 was cloned and co‐transfected into CNE2 and C666‐1 cells. This evidence concerns the gene ATF1 and nasopharyngeal carcinoma.