TFF2 and neoplasm: And it has also been implicated to play a vital role in regulating numerous pathophysiological actions related to cancer.6, 7, 8, 9 After combining specifically with the SP, one of the tachykinins, NK‐1R controls the tumor cell proliferation, migration, metastasis and angiogenesis.6, 7, 10 However, NK‐1R antagonists could block the function of SP/NK‐1R complex and induce apoptosis and death of cancer cells.