The MT1-MMP expressed on the membrane of the mesenchymal-like cancer cells also degrades the ECM, which is expressed through the degradation rate \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\varGamma _{_1}>0$$\end{document}Γ1>0. The gene discussed is MMP14; the disease is cancer.