Since the outcomes of these behavioral tests are greatly modified by the anxiety level of the animals, and the sst4-deficient mice have more anxious and depressive-like phenotye (Scheich et al. 2016), our findings might not only be explained by the direct inhibition of learning and locomotion by somatostatin via this receptor, but higher stress level could also be an influencing factor. Here, SSTR4 is linked to Anxiety.