VEGFA and Ehlers-Danlos syndrome, vascular type: These tensile forces lead to shear stress on cell membranes which have been shown to have the potential to treat the underlying cause of vascular ED by prompting increased expression of vascular endothelial growth factor (VEGF) [7], recruitment of perivascular stem cells and recruitment of endothelial progenitor cells [8], resulting in neovascularisation of penile arteries.