The results of Transwell assay showed that the invasion ability of GC cells in the miR-27a inhibitors + SFRP1-siRNA group was significantly higher than that of the miR-27a inhibitors + siRNA-NC group, and the number of invasive cells in the miR-27a inhibitors + SFRP1-siRNA group increased significantly (P < 0.05; Figure 7C,D). The gene discussed is SFRP1; the disease is gastric cancer.