HDAC1 and nasopharyngeal carcinoma: Mechanically, various type of HDACs including HDAC1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 were examined in TSA and ITSA-1-treated NPC cells, and we found that due to difference in the basic genetic backgrounds, poorly differentiated CNE2 (Epstein-Barr virus negative due to massive passage) and undifferentiated C666–1 (Epstein-Barr virus positive) displayed differentially HDACs expression properties.