Moreover, MuRF1 expression significantly correlates with the relative atrophy factor and with the type 2 fiber atrophy factor (AF-FAST) when considering T2DM and DM patients or DM patients alone (DM+T2DM: AF Pearson r = 0.59, p = 0.01, AF-FAST Pearson r = 0.48, p = 0.05; DM: AF Pearson r = 0.82, p = 0.0005, AF-FAST: Pearson r = 0.71, p = 0.007) (Fig 4C). The gene discussed is TRIM63; the disease is diabetes mellitus.