PML and acute promyelocytic leukemia: Notably, many of these host factors have been shown to either reside or transiently associate with promyelocytic leukaemia nuclear bodies (PML-NBs, also known as ND10; [9, 11, 17, 20–26]), which rapidly associate with and entrap infecting viral DNA (vDNA) as a component of the intrinsic antiviral immune response [9, 12, 17, 19, 27–31].