The brain and DC‐associated LAMP‐like molecule (BAD‐LAMP) is a member of the lysosome‐associated membrane glycoproteins and controls, together with UNC93B1, the trafficking of TLR9.72 It is expressed by pDCs, which produce the largest amount of type I IFNs in response to viral infections.73, 74 Indeed, in human pDCs, BAD‐LAMP co‐localizes with UNC93B1 from the ER to an endosomal hybrid compartment, the IRF‐SE, which expresses both VAMP3 and LAMP2. Here, UNC93B1 is linked to viral infectious disease.