Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the pathogenic expansion of the CAG tract beyond 35 repeats at the N‐terminus of the huntingtin (Htt) protein.95 Htt interacts with both anterograde and retrograde transport motor proteins.96, 97 For certain cargoes, the phosphorylation state of Htt plays a role in deciding the directions of their axonal transport.99 This evidence concerns the gene HTT and juvenile Huntington disease.