Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the pathogenic expansion of the CAG tract beyond 35 repeats at the N‐terminus of the huntingtin (Htt) protein.95 Htt interacts with both anterograde and retrograde transport motor proteins.96, 97 For certain cargoes, the phosphorylation state of Htt plays a role in deciding the directions of their axonal transport.99 Here, HTT is linked to Huntington disease.