CD4 and myeloid sarcoma: Because we observed that the L. reuteri strain 17938 inhibits the differentiations of naïve CD4+ T cells into TH1, TH2 (13), and TH17 cells in vitro (data not shown), we decided to “put this strain to the test” in the EAE model of MS, a condition mediated primarily by TH1 and TH17 cells (31).