The majority of histopathological reports were brief; they included only WHO grading and type, immunohistological markers (such as S100 and fibronectin), as well as cell surface receptors (e.g. Ki67 and HH3) in higher-grade meningiomas (15, 16) have been inadequately reported, hence it was difficult to perform detailed histopahological analyses. The gene discussed is PROKR2; the disease is meningioma.