TNFSF10 and breast adenocarcinoma: The human T-lymphoblastoid leukemia-derived cells (Jurkat), a human breast adenocarcinoma cell line (MDA-MB-231), and HeLa cells were exposed to different doses of TRAIL for 4 h, a time frame in which cells died readily but the single-cell mitochondria abundances remained largely unchanged (Supplementary Notes 1 and 2, Supplementary Figs. 1–4).