FBXO11 and chronic otitis media: FBXO11 is a candidate disease gene in human chronic otitis media with effusion (Segade et al., 2006; Rye et al., 2011a,b; Bhutta et al., 2017a,b; also see reviews by Rye et al., 2011a,b; Rye et al., 2012) and the Jeff (Fbxo11Jf/+) mutant mouse (Mouse Genome Informatics number 1862017) has conductive hearing loss and chronic otitis media (Hardisty et al., 2003; Hardisty-Hughes et al., 2006).