Consistent with these findings, Chen and colleagues [44] have reported that FOXK2 overexpression in lung cancer-derived cell lines leads to upregulation of E-cadherin and α-catenin along with downregulation of N-cadherin and vimentin (Figure 5), suggesting that FOXK2 might modulate the expression of epithelial and mesenchymal markers closely linked to the EMT process. This evidence concerns the gene FOXK2 and lung cancer.