It was found that rs11786030 (A > G) and rs2292779 (C > G), located in AGO2, resulting in decreased DFS (HR = 2.62; CI 1.41–4.88 and HR = 1.42; CI 1.06–1.92 for rs11786030 and rs2292779 respectively) as well as poor OS (HR = 2.41; CI 1.05–5.50 and HR = 2.94; CI 1.52–5.69 for rs11786030 and rs2292779 respectively) in breast cancer patients [21]. Here, AGO2 is linked to breast cancer.