We next assessed TM4SF18 expression in the pancreatic cancer cell lines Panc-1, MiaPaca-2, BxPC-3, AsPC1, and Capan-1, as well as the non-malignant human pancreatic ductal epithelium (HPDE) cell line by western blot analysis. Here, TM4SF18 is linked to familial pancreatic carcinoma.